Background : Hemosuccus Pancreaticus (HP) is a rare cause of upper gastrointestinal bleeding. It is characterized by intermittent bleeding from the major duodenal papilla through the main pancreatic duct. HP can be life-threatening, and if not properly addressed, it can lead to high mortality rates. This condition usually results from the rupture of a pseudoaneurysm of the splenic artery, which is a complication of pancreatitis. Although extremely rare, HP can also result from a true splenic artery aneurysm, making diagnosis even more challenging. Due to paucity of cases reported, there is limited knowledge about the disease. It is not easily recognized initially and is misdiagnosed as another cause of upper gastrointestinal bleeding. Prompt recognition is paramount for better management strategies.

Methods : A case report will be presented. The patient’s data were retrieved and reviewed from our MD Portal, St. Luke’s Medical Center electronic medical record.

Results : NA

Conclusions : Hemosuccus Pancreaticus is a challenging diagnosis. It should be considered in patients with upper gastrointestinal bleeding, especially in patients with pancreatitis. Angioembolization eliminates the need for surgery but bleeding recurrence is still high. This case report emphasizes the challenges in diagnosing and managing the case.  Presently, there is no standard management protocol for hemosuccus pancreatic due to a true splenic artery aneurysm. Angioembolization has been successful in the management but bleeding recurrence is reportedly high. In case of a failed endoscopic intervention, surgery is warranted.