Detailed Abstract
[E-poster - Biliary & Pancreas (Biliary Disease/Surgery)]
[EP 208] Outcome of Gallbladder Cancer: Experience from Tertiary Hepato-pancreatico-biliary Unit in a Lower Income Country
Duminda SUBASINGHE 1, Harshana PRIYAN 1, Harshana WIJAYALATHGE 1, Nilesh FERNANDOPULLE 1, Vihara DASSANAYAKE 2, Sivasuriya SIVAGANESH 1
1 Department of Surgery,Division of Hepatopancreaticobiliary Surgery, University of Colombo, SRI LANKA, 2 Department of Surgery,Division of Hepatopancreaticobiliary Surgery, University of Colombo, SRI LANKA
Background : Gallbladder cancer(GBCA) is a rare but aggressive biliary malignancy. It has poor prognosis due to advance stage at presentation. To describe the disease characteristics and outcomes of a cohort of GBCA
Methods : A retrospective analysis of prospectively maintained database for gallbladder cancer at an HPB division of a tertiary care center in Sri Lanka. There were 14 patients with GBCA between 2021-2023.
Results : The mean age was 60 years (range 43-73), with a male-to-female ratio of 1:3. The most common presentation was jaundice (n=4, 28.6%). Other presentations consisted of right upper quadrant pain (n=2,14.3%), epigastric discomfort (n=3,21.2%), dyspepsia (n=2,14.3%), cholangitis(n=1,7.1%), anorexia(n=1,7.1%), umbilical nodule(n=1,7.1%) . Loss of appetite and weight loss were observed in 71.4% (n=10) of patients. Comorbid gallstone disease was present in 43% (n=6) of cases. Radiological assessment revealed gallbladder masses in 7 (50%) patients and irregular eccentric thickening of the gallbladder in 1 patient (7.1%). Four (33.4%) patients underwent radical cholecystectomy with hepatoduodenal lymphadenectomy. There was no postoperative complications. Metastatic disease was observed in 71.4% (n=10) and all underwent palliative chemotherapy. Three patients(23%) underwent surgery are free of recurrence up-to-date.
Conclusions : The outlook for GBCA remains unfavourable in our centre due to metastatic disease and unresectable stage at presentation. Early detection, referral, and timely surgical resections can improve outcomes for affected patients.
Methods : A retrospective analysis of prospectively maintained database for gallbladder cancer at an HPB division of a tertiary care center in Sri Lanka. There were 14 patients with GBCA between 2021-2023.
Results : The mean age was 60 years (range 43-73), with a male-to-female ratio of 1:3. The most common presentation was jaundice (n=4, 28.6%). Other presentations consisted of right upper quadrant pain (n=2,14.3%), epigastric discomfort (n=3,21.2%), dyspepsia (n=2,14.3%), cholangitis(n=1,7.1%), anorexia(n=1,7.1%), umbilical nodule(n=1,7.1%) . Loss of appetite and weight loss were observed in 71.4% (n=10) of patients. Comorbid gallstone disease was present in 43% (n=6) of cases. Radiological assessment revealed gallbladder masses in 7 (50%) patients and irregular eccentric thickening of the gallbladder in 1 patient (7.1%). Four (33.4%) patients underwent radical cholecystectomy with hepatoduodenal lymphadenectomy. There was no postoperative complications. Metastatic disease was observed in 71.4% (n=10) and all underwent palliative chemotherapy. Three patients(23%) underwent surgery are free of recurrence up-to-date.
Conclusions : The outlook for GBCA remains unfavourable in our centre due to metastatic disease and unresectable stage at presentation. Early detection, referral, and timely surgical resections can improve outcomes for affected patients.
SESSION
E-poster
E-Session 03/21 ALL DAY