Background : Pancreatic duct disruption is a complex medical condition associated with various symptoms and complications. This research aimed to evaluate the efficacy of pancreatic duct stenting in managing pancreatic duct disruption and its impact on patient outcomes

Methods : The retrospective study was conducted on diagnosed cases of PPD on CT/MRI, unresolved peripancreatic pseudocyst, established cases of post-necresectomy pancreatico-cutanoeous fistula who had undergone endoscopic retrograde cholangiopancreatography (ERCP), and received pancreatic duct stent placement. Clinical features, laboratory parameters, radiological characteristics, and pancreatogram findings were assessed.

Results : The study included n=21 male patients with a mean age of 40.10±14.02 years. Among the patients, 71.43% had a history of alcoholism. In patients with a history of pancreatitis (n=11), 90.91% had one previous episode, and 9.09% had two prior episodes. Acute pancreatitis (47.62%) and pancreatic pseudocysts (28.57%) were the most common diagnoses. The primary site of the leak was often at the head and body of the pancreatic duct (19.05%). Sphincterotomy was performed in the majority of cases (95.21%), and a 5FR X 10cm stent was used in 33.33% of cases. Postoperative serum amylase and lipase levels significantly decreased. No postoperative complications were observed during hospitalization, and the average stay was 7.57 days. During the follow-up period, 9.52% of patients develop complications such as pancreatic abscess and moderate resolution of pancreatic pseudocyst.

Conclusions : Pancreatic duct stenting appears to be an effective intervention for managing pancreatic duct disruption.