Background : The development of postoperative pancreatic fistula remains the main risk factor for complications after pancreaticoduodenal resection. The issue of preventing the development of pancreatic fistula remains relevant and unresolved. The developed models that can warn about the risk of development are widely used in practice.

Methods : A retrospective evaluation of the validation of the developed models for calculating the risk of postoperative pancreatic fistula in patients operated on by a single team of surgeons was conducted at the National Cancer Institute of Ukraine.

Results : The study included 111 patients who underwent pancreaticoduodenal resection in the years 2020-2023 for malignant tumors of the pancreatic head, or periampullary zone. All patients were operated on by the same team of surgeons, which allows for a more objective assessment of the treatment results. There were 23 laparoscopic operations (20.7%) and 88 open operations (79.3%). In our practice, we used MDCalc (www.mdcalc.com/calc/10194/pancreatic-fistula-risk-score) to calculate the risk of postoperative pancreatic fistula. The " Negligible" group comprised 24 patients (21.6%), the "Low" group comprised 41 patients (36.9%), the "Intermediate" group comprised 44 patients (39.6%), and the "High" group comprised only 2 patients (1.8%). The results of the postoperative assessment showed that 47 (42.3%) patients had no fistula, 38 (34.2%) patients had biochemical fistula, 12 (10.8%) patients had grade B fistula, and 14 (12.6%) patients had grade C fistula.

Conclusions : Developing a model to prevent the development of postoperative pancreatic fistula is a significant step in understanding risk factors, but is questionable in clinical application.