Background : We sought to determine clinicopathological differences before and after surgery and clinical changes at 1-year follow-up based on BMI  25 kg/m2 in patients who underwent elective LC for gallstone disease.

Methods : From January 2020 to May 20222, a retrospective study was performed sixty-five patients who underwent elective LC for gallstone disease and received follow-up one year later. . Data analysis was divided into obese and non-obese group based on BMI 25 kg/m2.

Results : In the obese group, the ASA score and average value of Hb A1c were high, while the vitamin D titer was low. There was no difference in the average values of lipid profile, but there were many patients with high TG in obese group. The frequency of patients with high HDL was much more in the non-obese group. There was no difference in the results during and immediately after surgery. And there was no difference the two groups in the changes perceived by patients one year after cholecystectomy. But, sixteen patients responded that they were dissatisfied with surgery. Twelve patients said it was due to decreased digestive function, and four patients said it was due to discomfort in upper abdomen.

Conclusions : In the obese group, there were observations of ASA scores of 3 or higher, low vitamin D titers, and a higher frequency of high TG. While obesity did not cause differences in the surgical outcomes of cholecystectomy, more attention is needed in post-surgery healthcare management. It's essential to acknowledge that more patients than we anticipate experience discomfort after surgery.