Detailed Abstract
[E-poster - Biliary & Pancreas (Pancreas Disease/Surgery)]
[EP 145] Outcomes And Quality of Life among Chronic Pancreatitis Patients in a Tertiary Care Center in Sri Lanka
MALITH NANDASENA 1, MINIDU CHANDRAGUPTA 2, HASANGI GAMAGE 2, ASEL WIJESINGHE 2, S KALAIYUKAN 2, KASUN LAKMAL 2, ALOKA PATHIRANA 1
1 Department of Surgery , Department of Surgery, Faculty of Medical Sciences, University of Sri Jayewardenepura, SRI LANKA, 2 University Surgical Unit, University Surgical Unit, Colombo South Teaching Hospital, SRI LANKA
Background : Chronic Pancreatitis (CP) has multiple complications and decreases quality-of-life (QoL). This study aims to describe outcomes and compare QoL among CP patients managed surgically, endoscopically and conservatively in a tertiary care centre over 3 years.
Methods : A descriptive cross-sectional study was performed among follow-up CP patients. QoL index values were assessed using the validated EQ-5D-5L questionnaire. The significance of differences in distribution of index values among the three intervention categories were tested using the Kruskal-Wallis Test (p=0.05, CI=95%)
Results : Of 112 recruited CP patients (median age – 42, male - 73.2%), 62.5% (n=70) had alcohol as the etiology and 47.3% (n=53) had ever smoked. Half (n=56) were diabetic, 50.9% (n=57) had steatorrhea, 85.7% (n=96) had chronic abdominal pain and 10.7% (n=12) had obstructive jaundice at some point. 48.2% (n=54) had ERCP and stenting as the only intervention, 27.7% (n=31) underwent surgery and 24.1% (n=27) were managed conservatively. Mean QoL index values of post-surgical patients (0.73397) were lower than that of ERCP (0.85681) and conservatively managed (.91307) patients. The differences in distribution of QoL index values between post-surgical patients Vs conservatively managed and Vs ERCP patients were statistically significant (H (2) = 12.597, p=0.02).
Conclusions : The decrease in QoL index values as level of intervention escalated from conservative to endoscopic to surgical is likely due to increasing severity of disease necessitating such, with interventions having limited benefit in improving QoL.
Methods : A descriptive cross-sectional study was performed among follow-up CP patients. QoL index values were assessed using the validated EQ-5D-5L questionnaire. The significance of differences in distribution of index values among the three intervention categories were tested using the Kruskal-Wallis Test (p=0.05, CI=95%)
Results : Of 112 recruited CP patients (median age – 42, male - 73.2%), 62.5% (n=70) had alcohol as the etiology and 47.3% (n=53) had ever smoked. Half (n=56) were diabetic, 50.9% (n=57) had steatorrhea, 85.7% (n=96) had chronic abdominal pain and 10.7% (n=12) had obstructive jaundice at some point. 48.2% (n=54) had ERCP and stenting as the only intervention, 27.7% (n=31) underwent surgery and 24.1% (n=27) were managed conservatively. Mean QoL index values of post-surgical patients (0.73397) were lower than that of ERCP (0.85681) and conservatively managed (.91307) patients. The differences in distribution of QoL index values between post-surgical patients Vs conservatively managed and Vs ERCP patients were statistically significant (H (2) = 12.597, p=0.02).
Conclusions : The decrease in QoL index values as level of intervention escalated from conservative to endoscopic to surgical is likely due to increasing severity of disease necessitating such, with interventions having limited benefit in improving QoL.
SESSION
E-poster
E-Session 03/21 ALL DAY