Detailed Abstract
[E-poster - Liver (Transplantation)]
[EP 069] Risk factors for alcohol relapse after liver transplantation: young age and alcoholic liver cirrhosis
Ji Hoon JO1, Hyung Hwan MOON1, Young Il CHOI1, Dong Hoon SHIN1
1Department of Hepatobiliary and Pancreatic Surgery, Kosin University Gospel Hospital, Republic of Korea
Background : The breakthrough and contribution of hepatitis virus treatment have reduced liver cirrhosis caused by hepatitis. Unfortunately, alcoholic cirrhosis is filling the void. One of the biggest problems of liver transplantation due to alcoholic cirrhosis is alcohol relapse, which is commonly encountered in clinical practice.
Methods : From May 2015 to December 2022, 33 deceased donor liver transplantations (DDLTs) and 42 living donor liver transplantations (LDLTs) were performed. We excluded eleven cases of peri-operative deaths. We retrospectively reviewed these patient's demographic profiles, pre and post-liver transplant alcohol consumption history, smoking history, maritual, educational occupational status and post-transplant complication and laboratory data.
Results : Among sixty-four patients, 30 (46.8%) had pre-liver transplant alcohol drinking history. among the 30 patients, 19 (63.3%) had received liver transplants due to alcoholic liver cirrhosis. The rate of drinking alcohol after liver transplant was 9.3% (6/64), and all of them were patients who had drank alcohol before liver transplantation. (p=0.033) All six patients were liver transplant patients due to alcoholic cirrhosis. Age was related to alcohol consumption after 1liver transplantation. post-liver transplant alcohol consumption group was younger than those who do not drink alcohol. (p= 0.008, 45.1 vs 54.6 year-old)
Conclusions : Young patients with alcoholic cirrhosis are more likely to retake alcohol after liver transplantation. Appropriate evaluation and management before and after liver transplantation are considered essential for them.
Methods : From May 2015 to December 2022, 33 deceased donor liver transplantations (DDLTs) and 42 living donor liver transplantations (LDLTs) were performed. We excluded eleven cases of peri-operative deaths. We retrospectively reviewed these patient's demographic profiles, pre and post-liver transplant alcohol consumption history, smoking history, maritual, educational occupational status and post-transplant complication and laboratory data.
Results : Among sixty-four patients, 30 (46.8%) had pre-liver transplant alcohol drinking history. among the 30 patients, 19 (63.3%) had received liver transplants due to alcoholic liver cirrhosis. The rate of drinking alcohol after liver transplant was 9.3% (6/64), and all of them were patients who had drank alcohol before liver transplantation. (p=0.033) All six patients were liver transplant patients due to alcoholic cirrhosis. Age was related to alcohol consumption after 1liver transplantation. post-liver transplant alcohol consumption group was younger than those who do not drink alcohol. (p= 0.008, 45.1 vs 54.6 year-old)
Conclusions : Young patients with alcoholic cirrhosis are more likely to retake alcohol after liver transplantation. Appropriate evaluation and management before and after liver transplantation are considered essential for them.
SESSION
E-poster
E-Session 03/21 ALL DAY