Background : Although sexual functioning is an essential facet of LDLT patients QoL, risk factors for hypogonadism and erectile dysfunction are largely unknown. This is a problem that patients and health professionals are reluctant to discuss face to face.

Methods : An integrative literature review from electronic database was conducted to determine the incidence of sexual dysfunction in LDLT patients. Inclusion criteria including 1) patients aged 18 or over; and 2) using Female Sexual Function Index (FSFI) and International Index of Erectile Function (IIEF).

Results : Sexual dysfunction is characterized by disturbances in sexual desire and the psychophysiological changes associated with the sexual response cycle in men and women. QoL LDLT patients remain similar to the general population except had lower mental health scores. The result also shows that sex hormone disturbances are highly prevalent in patients after LT, even though the rate is higher in men. It indicates that mental health problems after LT are related to sexual function deterioration. On the Donor side, sexual functioning was lower at the evaluation phase and three months than at one-year post-donation: difficulty reaching orgasm, lower sexual desire, dissatisfaction with sexual life. However, there has been an improvement in sex hormone levels after LT in some instances, namely, normalization of estradiol levels and lowering prolactin and progesterone levels.

Conclusions : It is crucial to maintain high therapeutic adherence, thus ensuring a good outcome of the care received before and after the transplantation process. It help them for the early recovery phase may improve recovery and reduce distress regarding sexual functioning.