Background : Laparoscopic donor and recipient explant hepatectomy in living donor liver transplantation has been successfully performed in a few high-volume centers around the world, proving feasibility, safety, fast recovery, and aesthetics for liver donors and recipient.

Methods : We reported 27 first cases of pure laparoscopic donor hepatectomy and 8 cases underwent total laparoscopic explant hepatectomy in Vietnam performed at Department of Hepatopancreato-biliary Surgery at 108 Military Hospital from November 2017 to December 2023.

Results : In 27 donors, the mean operative time was 255,3 minutes, mean time for parenchyma resection was 71,6 minutes, mean blood loss was 245,3 mL. The patients were followed up for 3-20 months after surgery, complication rate was witnessed in 3 cases (11,1%), all of which were biliary leak, managed successfully with percutaneous drainage in 2 cases and reoperation in 1 case. In 8 recipients, mean time for laparoscopic explant hepatectomy 120,5 minutes. We noted no complication related with laparoscopic phase.

Conclusions : Our short-term outcome of pure laparoscopic donor hepatectomy proved this technique as a feasible and safe strategy for liver living donor and laparoscopic explant hepatectomy is indicated in selected recipients only.