Detailed Abstract
[BP Oral Presentation 1 - Biliary & Pancreas (Biliary Disease/Surgery)]
[BP OP 1-S1] Role of Minimally Invasive Approach in Reoperation for Postoperatively Diagnosed T2 Gallbladder Cancer: a Multicenter Cohort Study
Yeshong PARK 1, Jinju KIM 1, MeeYoung KANG 1, Boram LEE 1, Ho-Seong HAN 1, Dae Wook HWANG 2, Chang Moo KANG 3, Chi-Young JEONG 4, Wan-Jun KIM 5, Yoo-Seok YOON 1
1 Department of Surgery, Seoul National University Bundang Hospital, REPUBLIC OF KOREA, 2 Department of Surgery, Asan Medical Center, REPUBLIC OF KOREA, 3 Department of Surgery, Severance Hospital, REPUBLIC OF KOREA, 4 Department of Surgery, Gyeongsang National University Hospital, REPUBLIC OF KOREA, 5 Department of Surgery, Korea University Guro Hospital, REPUBLIC OF KOREA
Background : Although T2 gallbladder cancer (GBC) incidentally diagnosed after cholecystectomy requires additional resection, surgical approaches are technically difficult due to inflammatory adhesion or fibrosis around the hepatoduodenal ligament and gallbladder bed. This study aims to compare surgical and oncologic outcomes of open and minimally invasive reoperation for postoperatively diagnosed T2 GBC.
Methods : Through a multicenter retrospective cohort study involving five tertiary referral centers, patients who underwent open (n = 110) and laparoscopic (n = 38) reoperation for T2 GBC between November 2004 and October 2022 were analyzed. Short-term and long-term outcomes were compared between the two groups.
Results : Clinicopathological characteristics showed no difference between the open and laparoscopic groups. Liver resection was more often performed by open approach (101 (91.8%) vs. 21 (55.3%), P < 0.001). Compared to open surgery, laparoscopic reoperation was associated with shorter postoperative hospital stay (9.0 (8.0 – 10.0) vs. 6.0 (3.8 – 8.3), P < 0.001) and lower postoperative complication rate (24 (21.8%) vs. 1 (2.6%), P = 0.013). In subgroup analysis for patients who underwent liver resection, postoperative hospital stay was still longer in the open group (9.0 (8.0 – 10.0) vs. 6.0 (4.0 – 9.0), P = 0.004). There was no significant difference between the open and laparoscopy groups in 5-year disease-free survival (66.7% vs. 76.1%, P = 0.749) and overall survival rates (75.2% vs. 73.7%, P = 0.789).
Conclusions : This study suggests that laparoscopic reoperation for postoperatively diagnosed T2 GBC shows favorable postoperative outcomes and similar oncologic safety compared to open surgery.
Methods : Through a multicenter retrospective cohort study involving five tertiary referral centers, patients who underwent open (n = 110) and laparoscopic (n = 38) reoperation for T2 GBC between November 2004 and October 2022 were analyzed. Short-term and long-term outcomes were compared between the two groups.
Results : Clinicopathological characteristics showed no difference between the open and laparoscopic groups. Liver resection was more often performed by open approach (101 (91.8%) vs. 21 (55.3%), P < 0.001). Compared to open surgery, laparoscopic reoperation was associated with shorter postoperative hospital stay (9.0 (8.0 – 10.0) vs. 6.0 (3.8 – 8.3), P < 0.001) and lower postoperative complication rate (24 (21.8%) vs. 1 (2.6%), P = 0.013). In subgroup analysis for patients who underwent liver resection, postoperative hospital stay was still longer in the open group (9.0 (8.0 – 10.0) vs. 6.0 (4.0 – 9.0), P = 0.004). There was no significant difference between the open and laparoscopy groups in 5-year disease-free survival (66.7% vs. 76.1%, P = 0.749) and overall survival rates (75.2% vs. 73.7%, P = 0.789).
Conclusions : This study suggests that laparoscopic reoperation for postoperatively diagnosed T2 GBC shows favorable postoperative outcomes and similar oncologic safety compared to open surgery.
SESSION
BP Oral Presentation 1
Room B 3/21/2024 3:30 PM - 4:30 PM